WHO: initial analysis of Pakistani H5N1 suggests no dangerous mutations

first_imgJan 3, 2008 (CIDRAP News) – An official from the World Health Organization (WHO) today shared results of initial genetic sequencing tests on H5N1 avian influenza samples from a man who died of the disease in Pakistan that suggest the strain doesn’t have the capacity for widespread transmission.John Rainford, a WHO spokesman in Geneva, told CIDRAP News that the genetic sequencing involved two clinical samples from a 25-year-old man from the Peshawar area who was recently announced as the first confirmed human H5N1 case-patient and fatality in Pakistan.The man was part of a family cluster of suspected H5N1 cases which sparked global concern that the virus had mutated into a form that could enable widespread human-to-human transmission. However, the WHO said in a previous statement that while the Pakistani cases suggest a rare instance of human-to-human transmission, the virus did not spread beyond the family.Rainford said preliminary sequencing of the hemagglutinin and neuraminidase genes from the specimens was performed at the WHO collaborating center in London. Tests completed so far show the hemagglutinin amino acid sequence is identical to some of the recent clade 2.2 viruses that have been isolated from chickens in other outbreaks in the region, he said.WHO virologists say the findings, along with recent field investigations, suggest that the H5N1 viruses in Pakistan have not gained the capacity for widespread human-to-human transmission, reported Rainford.In addition, neither analysis by WHO collaborating scientists of the neuraminidase gene nor partial sequencing of the M2 gene shows mutations that are known to be associated with antiviral resistance, Rainford said. “This indicates oseltamivir and amantadine should be inhibitory for the virus,” he added.Rainford said full genome sequencing is in progress.The WHO praises Pakistan’s timely investigation and management of suspected H5N1 cases, Rainford said. “[This] has provided reassurance about the lack of community H5N1 transmission, an effort that deserves appreciation and support.”In other avian flu developments, the WHO yesterday confirmed two fatal H5N1 cases in women from Egypt whose deaths were recently reported in the media. One was a 25-year-old from Dakahlyah governorate who got sick Dec 26, was hospitalized the next day, and died Dec 30. The other was a 36-year-old from Menofia governorate who became ill Dec 26, was hospitalized Dec 29, and died 2 days later.The two women are listed as Egypt’s 42nd and 43rd avian flu case-patients, and their deaths are recorded as the country’s 17th and 18th fatalities from the disease.The WHO reported that investigators have found no epidemiologic link between the 36-year-old and another woman from Menofia governorate whose H5N1 illness was recently confirmed by the WHO. That 22-year-old woman was previously reported to be recovering in intensive care.Also, the WHO today confirmed the death of a 50-year-old Egyptian woman who was previously confirmed as the country’s 40th H5N1 case-patient on Dec 28. The woman, from Domiatt governorate, was hospitalized Dec 24 and died Dec 31. She is listed as Egypt’s 19th avian flu death.In its announcements about the women, the WHO said all three had contact with sick or dead poultry before they became ill.Elsewhere, a veterinary official in Vietnam told Tuoi Tre newspaper that the country’s most recent H5N1 patient, a 4-year-old boy from Son La province who died of the disease on Dec 16, may have contracted the virus from a wild bird, according to a Bloomberg News report today.That report says the official, Van Dang Ky, speaking at a national conference on bird flu control in Hanoi yesterday, noted that the boy’s family had brought home some wild birds from a hunting trip and also that samples from poultry in the area where the boy lived tested negative for the H5N1 virus.See also:Dec 27 CIDRAP News story “WHO confirms H5N1 case in Pakistan cluster”last_img read more

Sports video games to try during quarantine

first_imgThere’s simply no way around it, it’s a tough time to be a sports fan. All large gatherings necessary for professional and college sports are banned. Outside of the UFC, it seems like there is little hope that live sports will again be on the televisions of fans anytime soon. Football: Top recruits, developing talent leave Badgers primed to reload in key positions for 2020 seasonAs the 2020 NFL draft approaches at the end of next month, Badgers Jonathan Taylor, Zack Baun, Chris Orr and Read…Even with this being the case, we still have to get our daily fix of sports action. For those of you who may have already exhausted your supply of old highlights and classic games, sports video games have the potential to fill this gaping void. In fact, they may be even better at passing the time as they engage you in the action directly rather than simply passing you by on a screen. With that being said, here is our list of the top three sports video games to try out during quarantine in order to fill your need for sports content.1. NCAA Football 14Arguably the crown jewel of video games about sports and of video games generally, NCAA Football 14 is the last in a line of games that defined many childhoods of college football fans around the nation. Surprisingly enough, the gameplay holds up quite well, even after nearly seven years since its release. UW Athletics: Top Badger sports moments to enjoy during COVID-19 pandemicWith live sports absent for the time being, sports fans worldwide have been isolated at home with what feels like Read…If there is one problem with this game, it is how limited the access to it is. Unless you currently have a copy, as well as an Xbox 360 or Playstation 3 to play it on, you’ll have to pay a pretty penny to enjoy this instant classic. The game currently retails for an astounding 160 dollars on Amazon, depending on which console you would have to purchase it for. For anyone who does still have access though, this game provides hours and hours of entertainment for any college football fan. Specifically, both the dynasty and road to glory modes are massive time sinks. There is still nothing like leading a team like Northern Illinois to five consecutive national titles after joining the Big Ten. You can even begin your career as a player in high school and try to earn a spot on the Badgers’ roster. Any way you want to play it, this game will provide a heavy sense of nostalgia for those who enjoyed it many years ago. 2. Rocket League Yes, technically this is not a sports game as they are traditionally defined. It is loosely based on soccer but, for those who have never heard of it, is played with cars instead of humans. If you’re able to put realism on hold, this game is a thrilling and ultra-competitive test of anyone’s skills on the sticks. Forward Madison FC: Flamingos soldier on in midst of season-suspending pandemicThe Forward Madison FC Flamingos had a solid inaugural season, finishing with a 12–7–9 record and the distinction of being Read…If you find yourself beginning to play in ranked playlists, prepare to see the best and the worst of humanity brought out on the field. In one game to the next, you can have your own teammate relentlessly trash talk you for missing a shot or have them be an amazing person you choose to party up with and take on multiple opponents. Even Forward Madison FC has gotten in on the action, as they have had their own players go head-to-head online against those of other teams in their division. 3. Wii SportsAnother classic rounds out our top three sports games to keep you entertained during what feels like a period of eternal quarantine. This one is truly the jack of all trades, as it allows you to pick any sport you would like to focus on. In few other games can you quickly switch between a heavyweight boxing match and a round of bowling all in the span of just a few minutes. Especially if you’re locked in with multiple people, game modes like tennis and golf provide a ton of opportunities to make this a household event. Once again, it is not the most realistic, but this game provides a more laid back experience for those who want to avoid the competitiveness of a ranked Rocket League match or a national championship matchup in NCAA 14.last_img read more

Kobe Bryant reaction: Athletes react to death of Lakers legend

first_imgFormer Lakers star Kobe Bryant and his 13-year-old daughter were among nine people killed in a helicopter crash Sunday in Calabasas. The news rattled the sports world and led to instant reaction on social media: AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREUCLA alum Kenny Clark signs four-year contract extension with PackersFormer UCLA basketball player Shareef O’Neal, the son of Shaq, also shared the interaction he had with Kobe this morning. Newsroom GuidelinesNews TipsContact UsReport an Errorcenter_img We are providing free access to this article. Please consider supporting local journalism like this by purchasing a subscription.last_img read more

Five star KCCA a point away from retaining Uganda league title

first_imgKCCA striker Sserunkuma. PHOTO KCCA MEDIAKampala,Uganda | KCCA|  KCCA moved to within a point of retaining their Azam Uganda Premier League title following a commanding victory over Kirinya Jinja at Lugogo on Saturday.Derrick Nsibambi scored a brace in addition to further strikes from Sulaimon Akinyemi, Geoffrey Sserunkuma and Noel Nasassira in the 5-1 victory.Coach Mike Mutebi named youngsters Mustapha Kizza and Peter Magambo in a lineup that had Douglas Kisembo in goal while league leading striker Geoffrey Sserunkuma was partnered with in-form Derrick Nsibambi upfront.Victory consequently moved KCCA to 57 points, five ahead of nearest challengers. Villa who also won against Soana. With three games left, KCCA now require to only avoid defeat against Lweza in the next encounter on Tuesday to retain their crown.READ FULL STORY HEREShare on: WhatsApplast_img read more